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Because of the frequent occurrence of local complications and/or the presence of a chronic course of the disease with continuous activity not responding to medical treatment, the majority of patients with CD require surgery with time (Munkholm et?al, 1993, 1995; Louis et?al, 2001; Schwartz et?al, 2002; Carter et?al, 2004). After 20?years, most patients with CD have been operated on at least once (
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